Kode Mata Kuliah | KI4162 / 3 SKS |
---|
Penyelenggara | 105 - Kimia / FMIPA |
---|
Kategori | Kuliah |
---|
| Bahasa Indonesia | English |
---|
Nama Mata Kuliah | Struktur dan Rekayasa Protein | Structure and Engineering of Protein |
---|
Bahan Kajian | - Penentuan Struktur Protein dengan XRD, NMR, CryoEM
- Visualisasi Struktur Protein
- Analisis Struktur Protein dengan berbagai Basis Data dan Perangkat Lunak
- Famili dan Motif Protein
- Faktor untuk Pelipatan Protein
- Asam Amino untuk Stabilitas, Kelarutan, Aktivitas, dan Fisikokimia lain suatu protein
- Teknik Rekayasa Protein berbasis Mutasi Terarah dan Acak
- Teknik Rekayasa Protein berbasis Evolusi Terarah
- Teknik Rekayasa Protein berbasis Modifikasi Kimia dan Bioortogonalitas
- Karakterisasi dalam Rekayasa Protein berbasis LC-MS
- Presentasi Kasus Rekayasa Protein Berbasis Struktur
| - Determination of Protein Structure by XRD, NMR, CryoEM
- Protein Structure Visualization
- Protein Structure Analysis with various Databases and Software
- Protein Families and Motifs
- Factors for Protein Folding
- Amino Acids for Stability, Solubility, Activity, and other Physicochemistry of a protein
- Directed and Random Mutation-based Protein Engineering Techniques
- Directed Evolution-based Protein Engineering Techniques
- Protein Engineering Techniques based on Chemical Modification and Bioorthogonality
- Characterization in LC-MS based Protein Engineering
- Case Presentation of Structure-Based Protein Engineering
|
---|
Capaian Pembelajaran Mata Kuliah (CPMK) | - Mahasiswa mengenal metode-metode yang digunakan untuk menentukan struktur protein dan visualisasi struktur protein
- Mahasiswa mampu menjelaskan berbagai informasi yang terkandung dalam struktur protein dari basis data PDB
- Mahasiswa mampu menjelaskan bagian-bagian protein yang dapat direkayasa untuk menghasilkan protein dengan fungsi yang diinginkan
- Mahasiswa mampu menjelaskan teknik rekayasa protein berbasis mutasi terarah dan acak
- Mahasiswa mampu menjelaskan teknik rekayasa protein berbasis evolusi terarah
- Mahasiswa mampu menjelaskan teknik rekayasa protein berbasis modifikasi kimia dan bioortogonalitas
- Mahasiswa mengenal teknik karakterisasi dalam rekayasa protein berbasis LC-MS
- Mahasiswa dapat membuat bahan presentasi ilmiah yang berkualitas
- Mahasiswa mampu memformulasikan dan mempresentasikan gagasan ilmiah terkait rekayasa protein
- Mahasiswa mampu bekerjasama dalam kelompok dalam studi kasus dan presentasi kelompok terkait rekayasa protein
- Mahasiswa memahami prinsip dasar setiap program/perangkat lunak yang digunakan untuk menganalisis struktur protein maupun untuk rekayasa protein berbasis struktur
| - Students become familiar with the methods used to determine protein structure and visualize protein structure
- Students are able to explain various information contained in protein structures from the PDB database
- Students are able to explain the parts of proteins that can be engineered to produce proteins with the desired function
- Students are able to explain protein engineering techniques based on directed and random mutations
- Students are able to explain protein engineering techniques based on directed evolution
- Students are able to explain protein engineering techniques based on chemical modification and bioorthogonality
- Students become familiar with characterization techniques in LC-MS based protein engineering
- Students can make quality scientific presentation materials
- Students are able to formulate and present scientific ideas related to protein engineering
- Students are able to work together in groups on case studies and group presentations related to protein engineering
- Students understand the basic principles of each program/software used to analyze protein structures and for structure-based protein engineering
|
---|
Metode Pembelajaran | Tatap muka (kuliah), tugas, dan presentasi | Face to face (lectures), assignments and presentations |
---|
Modalitas Pembelajaran | Visual, auditorial, dan kinestetik.
Sinkronous (luring dan daring) dan asinkonous. | Visual, auditory, and kinesthetic.
Synchronous (offline and online) and asynchronous. |
---|
Jenis Nilai | ABCDE |
---|
Metode Penilaian | Ujian dan tugas | Exams and assignments |
---|
Catatan Tambahan | | |
---|