| Kode Mata Kuliah | KI5077 / 3 SKS |
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| Penyelenggara | 248 - Pengajaran Kimia / FMIPA |
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| Kategori | Kuliah |
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| Bahasa Indonesia | English |
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| Nama Mata Kuliah | Makromolekul dan Sintesis Organik | Macromolecule and Organic Synthesis |
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| Bahan Kajian | - Struktur, tatanama, sifat fisik, sintesis dan reaksi kimia senyawa amina dan turunannya (sintesis Gabriel, aminasi reduktif, penataan ulang Hoffmann, penataan ulang Curtius, eliminasi Hoffmann).
- Struktur, sifat fisik dan reaksi kimia asam amino dan protein, penentuan urutan asam amino pada rantai polipeptida, sintesis polipeptida.
- Struktur, sifat fisik dan reaksi kimia karbohidrat.
- Struktur, sifat fisik dan reaksi kimia senyawa bahan alam: asam nukleat dan lipid (asam lemak, trigliserida, fosfolipid, terpen, terpenoid, dan steroid).
- Pengenalan analisis retrosintesis untuk sintesis senyawa organik sederhana
| - Structure, nomenclature, physical properties, synthesis, and chemical reactions of amine compounds and their derivatives (Gabriel synthesis, reductive amination, Hoffmann rearrangement, Curtius rearrangement, Hoffmann elimination).
- Structure, physical properties, and chemical reactions of amino acids and proteins, determination of amino acid sequence in polypeptide chains, polypeptide synthesis.
- Structure, physical properties, and chemical reactions of carbohydrates.
- Structure, physical properties, and chemical reactions of natural compounds: nucleic acids and lipids (fatty acids, triglycerides, phospholipids, terpenes, terpenoids, and steroids).
- Introduction to retrosynthetic analysis for the synthesis of simple organic compounds.
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| Capaian Pembelajaran Mata Kuliah (CPMK) | - Mampu menjelaskan sifat fisik senyawa organik melalui penggambaran struktur molekul, struktur resonansi, konformasi, dan/atau stereokimianya.
- Mampu menentukan urutan asam amino penyusun polipeptida dan menguraikan sintesis polipeptida dari asam-asam amino penyusunnya melalui konsep proteksi-aktivasi dan SPPS (solid phase peptide synthesis).
- Mampu menjelaskan sifat fisik dan kimia senyawa asam nukleat, karbohidrat, dan lipid melalui penggambaran struktur maupun reaksi dan/atau mekanisme reaksi kimia pada senyawa organik tersebut.
- Mampu mengomunikasikan secara tulisan dan/atau lisan hasil eksperimen dan/atau hasil penelusuran literatur dengan mengedepankan etika dan kejujuran.
- Mampu menguraikan analisis retrosintesis dan sintesis senyawa organik sederhana dengan menggunakan reaksi-reaksi substitusi, adisi dan eliminasi.
- Mampu menyampaikan hasil eksperimen dan/atau hasil penelusuran literatur secara tulisan dan/atau lisan dengan mengedepankan etika dan kejujuran.
| - Able to explain the physical properties of organic compounds through the depiction of molecular structure, resonance structure, conformation, and/or stereochemistry.
- Able to determine the sequence of amino acids composing polypeptides and describe the synthesis of polypeptides from their constituent amino acids through the concepts of protection-activation and SPPS (solid phase peptide synthesis).
- Able to explain the physical and chemical properties of nucleic acids, carbohydrates, and lipids through the depiction of their structure as well as the reactions and/or reaction mechanisms of these organic compounds.
- Able to communicate experiment results and/or literature review findings in writing and/or verbally, emphasizing ethics and honesty.
- Able to describe retrosynthetic analysis and the synthesis of simple organic compounds using substitution, addition, and elimination reactions.
- Able to present experiment results and/or literature review findings in writing and/or verbally, emphasizing ethics and honesty.
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| Metode Pembelajaran | Ceramah
Tutorial
Diskusi, presentasi kelompok
Praktikum | Lecture
Tutorial
Discussion, group presentation
Practical/lab work |
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| Modalitas Pembelajaran | Luring Sinkron
Daring Asinkron
Praktikum di laboratorium | Offline Synchronous
Online Asynchronous
Laboratory practical (Lab work) |
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| Jenis Nilai | ABCDE |
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| Metode Penilaian | Nilai Akhir = 75% x ((UTS (35%) + UAS (35%) + tugas presentasi 20% + rata-rata tugas mandiri dan Kuis (10%)) + 25% x nilai praktikum
INDEKS NILAI: 75 ≥ A; 75 < AB ≤ 68; 68 < B ≤ 60; 60 < BC ≤ 55; 55 < C ≤ 50; 50 < D ≤ 45; 45 < E | Final Grade = 75% x ((midterm Exam (35%) + final Exam (35%) + presentation assignment (20%) + average of independent assignments and quizzes (10%)) + 25% x lab work grade
GRADE INDEX: 75 ≥ A; 75 < AB ≤ 68; 68 < B ≤ 60; 60 < BC ≤ 55; 55 < C ≤ 50; 50 < D ≤ 45; 45 < E |
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| Catatan Tambahan | | |
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