| Kode Mata Kuliah | FA5053 / 5 SKS |
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| Penyelenggara | 207 - Farmasi / SF |
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| Kategori | Kuliah |
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| Bahasa Indonesia | English |
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| Nama Mata Kuliah | Bioteknologi Molekuler | Molecular Biotechnology |
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| Bahan Kajian | - Alur produksi produk biologi (pengembangan genetika – teknologi DNA rekombinan & manipulasi ekspresi gen di prokariot dan eukariot)
- Alur produksi produk biologi (pembuatan, karakterisasi & pemeliharaan bank sel)
- Produksi bahan baku protein (Fermentasi, isolasi, purifikasi, karakterisasi)
- Spesifikasi, metode farmakope dan regulasi untuk bahan baku dan produk jadi produk biologi (termasuk CPOB-produk biologi)
- Praktikum : Persiapan dan sterilisasi bahan dan alat untuk produksi protein rekombinan
- Praktikum : Penyiapan DNA dan kloning gen
- Praktikum : Transformasi materi genetik dan karakterisasi transforman
- Praktikum : Produksi, pemurnian dan karakterisasi protein rekombinan
| - Production pathway of biological products (genetic development – recombinant DNA technology & manipulation of gene expression in prokaryotes and eukaryotes)
- Production pathway of biological products (creation, characterization & maintenance of cell banks)
- Production of protein raw materials (Fermentation, isolation, purification, characterization)
- Specifications, pharmacopeial methods, and regulations for raw materials and finished biological products (including GMP for biological products)
- Laboratory practical : Preparation and sterilization of materials and equipment for recombinant protein production
- Laboratory practical : DNA preparation and gene cloning
- Laboratory practical : Genetic material transformation and characterization of transformants
- Laboratory practical : Production, purification, and characterization of recombinant proteins
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| Capaian Pembelajaran Mata Kuliah (CPMK) | - Mampu menjelaskan alur produksi dan karakterisasi produk biologi, khususnya protein
- Mampu mendeskripsikan parameter mutu produk biologi dalam kaitannya dengan pemenuhan regulasi produk biologi
- Mampu merancang dan menyusun metode untuk tahapan pekerjaan produksi protein rekombinan
- Mampu melakukan pekerjaan bioteknologi dasar untuk produksi bahan baku protein rekombinan dari hulu hingga hilir
- Mampu melakukan metode pengujian untuk karakterisasi parameter mutu produk protein rekombinan pada tingkat DNA dan protein
- Mampu menganalisa, menafsirkan data hasiil metode uji bioteknologi dasar dan memberikan rekomendasi penyelesaian masalah
| - Able to explain the production flow and characterization of biological products, particularly proteins
- Able to describe the quality parameters of biological products in relation to regulatory compliance
- Able to design and develop methods for the stages of recombinant protein production work
- Able to perform basic biotechnology tasks for the production of recombinant protein raw materials from upstream to downstream
- Able to carry out testing methods for the characterization of recombinant protein product quality parameters at the DNA and protein levels
- Able to analyze and interpret data from basic biotechnology methods/tests and provide recommendations for problem-solving
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| Metode Pembelajaran | Kuliah, diskusi, praktikum, tugas terstruktur (Presentasi, case study), tugas mandiri (studi literatur) | lecture, discussion, structured assignment (presentation, case study), individual assignment (literature study), laboratory practical |
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| Modalitas Pembelajaran | Visual, audiovisual, Praktek/kinestetik, sinkron, asinkron | visual, auditorial, practice/ kinesthetic, synchronous, asynchronous |
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| Jenis Nilai | ABCDE |
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| Metode Penilaian | UTS, UAS, Kuis, Tugas/Presentasi , Ketrampilan, pelaporan hasil praktikum (tertulis/Presentasi) | mid-exam, final exam, quiz, assignment/ presentation, skill assessment, laboratory practice report |
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| Catatan Tambahan | | |
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