| Kode Mata Kuliah | KI5261 / 3 SKS |
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| Penyelenggara | 205 - Kimia / FMIPA |
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| Kategori | Kuliah |
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| Bahasa Indonesia | English |
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| Nama Mata Kuliah | Metabolisme | Metabolism |
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| Bahan Kajian | - Tinjauan metabolisme
- Senyawa berenergi tinggi
- Bioenergetika dan termodinamika
- Reaksi oksidasi-reduksi biologi
- Model kasus jalur reaksi terang fotosintesis (pengubahan energi sinar matahari menjadi energi kimia ATP dan potensial kimia NADPH) – mekanisme aliran elektron (linear dan lingkar)
- Model kasus jalur reaksi gelap fotosintesis (fiksasi/asimilasi karbondioksida dan pembentukan glukosa) – mekanisme penangkapan karbon dan pembentukan biomolekul
- Organisasi supramolekul fotosistem II: struktur, fungsi, dan pengendalian kompleks pemanen cahaya II dan pusat reaksi P680
- Kompleks mangan pemecah molekul air
- Organisasi molekul sitrokrom bf dan interaksi dengan plastosianin
- Plastosianin: interaksi-interkasi/perakitan baik dengan sitokrom bf ataupun dengan fotosistem I
- Organisasi supramolekul fotosistem I: struktur, fungsi, dan pengendalian kompleks pemanen cahaya dan pusat reaksi P700
- Kompleks feredoksin-NADH reduktase
- Kompleks mirip NADH dehidrogenase: interaksi-interkasi/perakitan baik dengan sitokrom bf ataupun dengan fotosistem I
- Kompleks ATP sintase kloroplas
- Fiksasi karbon pada sistem tanaman C3, C4, dan CAM
- Fiksasi karbon pada sistem bakteri dan sianobakteri: karboksisom
- Fiksasi karbon pada sistem alga dan lumut: pirenoid
- Biosintesi gula
| - Overview of metabolism
- High-energy compounds
- Bioenergetics and thermodynamics
- Biological oxidation–reduction reactions
- Case study of the light reactions of photosynthesis (conversion of solar energy into chemical energy in the form of ATP and the chemical potential of NADPH): mechanisms of electron flow (linear and cyclic)
- Case study of the dark reactions of photosynthesis (carbon dioxide fixation/assimilation and glucose formation): mechanisms of carbon capture and biomolecule formation
- Supramolecular organization of photosystem II: structure, function, and regulation of the light-harvesting complex II and the P680 reaction center
- Manganese complex involved in water-splitting
- Molecular organization of the cytochrome b6f complex and its interaction with plastocyanin
- Plastocyanin: interactions/assembly with both the cytochrome b6f complex and photosystem I
- Supramolecular organization of photosystem I: structure, function, and regulation of the light-harvesting complex and the P700 reaction center
- Ferredoxin–NADP⁺ reductase complex
- NADH dehydrogenase-like complex: interactions/assembly with both the cytochrome b6f complex and photosystem I
- Chloroplast ATP synthase complex
- Carbon fixation in C3, C4, and CAM plant systems
- Carbon fixation in bacterial and cyanobacterial systems: carboxysomes
- Carbon fixation in algal and moss systems: pyrenoids
- Sugar biosynthesis
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| Capaian Pembelajaran Mata Kuliah (CPMK) | - Mahasiswa memahami prinsip-prinsip katabolisme (degradasi) dan anabolisme (biosintesis), mampu menunjukkan interkoneksi metabolit, dan merunut jalur metabolisme utuh.
- Mahasiswa memahami prinsip-prinsip katabolisme (degradasi) dan anabolisme (biosintesis), mampu menunjukkan interkoneksi metabolit, dan merunut jalur metabolisme utuh.
- Mahasiswa mampu mengintegrasikan hukum-hukum energi di dalam perubahan-perubahan metabolit di dalam jalur metabolisme.
- Mahasiswa mampu mengolah informasi jalur metabolisme baik antar molekul berbeda di dalam satu organisme maupun antar organisme berbeda.
- Mahasiswa mampu mencari dan mendapatkan literatur primer (publikasi) bermutu terbaru terkait struktur, fungsi, dan pengendalian biomolekul pada suatu metabolisme.
- Mahasiswa mampu mengintegrasikan informasi dari berbagai sumber literatur primer dalam menjelaskan temuan runutan jalur metabolisme.
- Mahasiswa mampu mengkomunikasikannya secara lisan publikasi terbaru terkait struktur, fungsi, dan pengendalian biomolekul pada suatu metabolisme dalam model seminar kecil.
- Mahasiswa secara berkelompok mampu merangkum dan menuliskan kembali intisari kumpulan publikasi terbaru dalam satu cerita model kasus metabolisme
- Mahasiswa mampu mengembangkan dasar teori dalam suatu jalur metabolisme untuk membuka kegiatan penelitian baru.
| - Students understand the principles of catabolism (degradation) and anabolism (biosynthesis), are able to demonstrate the interconnections among metabolites, and can trace complete metabolic pathways.
- Students are able to identify the structures and functions of metabolite molecules and their transformations within a metabolic pathway.
- Students are able to integrate the laws of energy into the changes of metabolites occurring within metabolic pathways.
- Students are able to process information on metabolic pathways, both among different molecules within a single organism and across different organisms.
- Students are able to search for and obtain high-quality, up-to-date primary literature (publications) related to the structure, function, and regulation of biomolecules in metabolism.
- Students are able to integrate information from various primary literature sources to explain findings related to metabolic pathway sequences.
- Students are able to communicate recent publications related to the structure, function, and regulation of biomolecules in metabolism orally in a small seminar setting.
- Students, working in groups, are able to summarize and rewrite the key points of a collection of recent publications into a coherent metabolic case-study narrative.
- Students are able to develop theoretical foundations within a metabolic pathway to initiate new research activities.
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| Metode Pembelajaran | Ceramah, strudi literatur, presentasi, dan/atau kerja kelompok | Lectures, literature studies, presentations, and/or group work |
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| Modalitas Pembelajaran | Visual dan auditorial; Sinkronous dan/atau asinkronous | Visual and auditory; synchronous and/or asynchronous |
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| Jenis Nilai | ABCDE |
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| Metode Penilaian | Ujian, Tugas, Laporan/Buku reviu | Examinations, assignments, reports/review books |
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| Catatan Tambahan | | |
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