| Kode Mata Kuliah | KI4263 / 3 SKS |
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| Penyelenggara | 105 - Chemistry / FMIPA |
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| Kategori | Lecture |
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| Bahasa Indonesia | English |
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| Nama Mata Kuliah | Transformasi karbohidrat | Carbohydrate Transformation |
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| Bahan Kajian | - Pengantar glikosains
- Struktur bentuk rantai terbuka gugus pereduksi dan reaksi gugus karbonil
- Subtsitusi nukleofil pada pusat anomer
- Konformasi monosakarida
- Struktur primer dan konformasi oligosakarida dan polisakarida
- Hidrolisis glikan yang dikatalisis enzim (keluarga glikosil hidrolase)
- Transfer glikosil yang dikatalisis enzim (keluarga glikosil transferase)
- Tren riset karbohidrat
| - Introduction to glycoscience
- The structure of the open chain form of the reducing group and the reaction of the carbonyl group
- Nucleophile substitution at the anomeric center
- Monosaccharide conformation
- Primary structure and conformation of oligosaccharides and polysaccharides
- Enzyme-catalyzed hydrolysis of glycans (glycosyl hydrolase family)
- Enzyme-catalyzed glycosyl transfer (glycosyl transferase family)
- Carbohydrate research trends
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| Capaian Pembelajaran Mata Kuliah (CPMK) | - Mahasiswa mengetahui dan memahami peta jalan transformasi glikosains pada energi, kesehan dan sains material.
- Mahasiswa mampu mengidentifikasi struktur stereokimia gula dan kereaktifannya pada reaksi adisi nukleofilik pada gugus karbonil gula.
- Mahasiswa memahami reaksi pada karbon anomer gula untuk tujuan modifikasi strukturnya
- Mahasiswa mampu analisis perbedaan konformasi karbohidrat dengan molekul organik lainnya.
- Mahasiswa memahami isolasi, identifikasi, penentuan struktur dan konformasi olisakarida dan polisakarida
- Mahasiswa memahami prinsip dan mekanisme kerja enzim keluarga glikosil hidrolase
- Mahasiswa memahami prinsip dan mekanisme kerja enzim keluarga glikosil transferase
- Mahasiswa mampu mencari dan mendapatkan literatur primer (publikasi) bermutu terbaru terkait karborhidrat dan transformasinya melalui reaksi kimia atau enzimatik.
- Mahasiswa mampu membaca dan menjelaskan literatur primer (publikasi) bermutu terbaru terkait karborhidrat dan transformasinya melalui reaksi kimia atau enzimatik.
- Mahasiswa mampu mengkomunikasikan literatur primer (publikasi) bermutu terbaru terkait karborhidrat dan transformasinya melalui reaksi kimia atau enzimatik.
- Mahasiswa mampu memberi penilaian dan menjelaskan arah perkembangan transformasi karbohidrat dari literatur primer (publikasi) bermutu terbaru.
| - Students know and understand the roadmap for glycoscience transformation in energy, health and materials science.
- Students are able to identify the stereochemical structure of sugar and its reactivity in nucleophilic addition reactions to the sugar carbonyl group.
- Students understand reactions on the anomeric carbon of sugar for the purpose of modifying its structure
- Students are able to analyze differences in carbohydrate conformation with other organic molecules.
- Students understand the isolation, identification, structure and conformation determination of olisaccharides and polysaccharides
- Students understand the principles and mechanisms of action of the glycosyl hydrolase family enzymes
- Students understand the principles and mechanisms of action of the glycosyl transferase family enzymes
- Students are able to search for and obtain the latest quality primary literature (publications) related to carbohydrates and their transformation through chemical or enzymatic reactions.
- Students are able to read and explain the latest quality primary literature (publications) related to carbohydrates and their transformation through chemical or enzymatic reactions.
- Students are able to communicate the latest quality primary literature (publications) related to carbohydrates and their transformation through chemical or enzymatic reactions.
- Students are able to assess and explain the direction of development of carbohydrate transformation from the latest quality primary literature (publications).
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| Metode Pembelajaran | Ceramah, studi literatur, dan/atau presentasi | Lectures, literature studies, and/or presentations |
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| Modalitas Pembelajaran | Visual dan auditorial; Sinkronous dan/atau asinkronous | Visual and auditory; Synchronous and/or asynchronous |
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| Jenis Nilai | ABCDE |
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| Metode Penilaian | Ujian, Tugas, Laporan | Exams, Assignments, Reports |
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| Catatan Tambahan | | |
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